Table 1. NSV triggers the production of inflammatory mediators in primary microglia via multiple non-overlapping signalling pathways.
Mediator | UNC93b1-dependent | MyD88-dependent | IRF7-dependent |
---|---|---|---|
IL-12p40 | + | + | − |
CCL2 | − | +/− | − |
CXCL13 | + | + | +* |
IFNα | − | − | + |
Inhibitory.