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. 2012 Jul 1;17(1):119–140. doi: 10.1089/ars.2012.4612

FIG. 4.

FIG. 4.

Hydrogen atom donation to carbon-centered radicals. Simple species containing an SH group such as H2S, HS-, HS-SH, and HSS- excel at undoing the damage inflicted to biomolecules by free radicals through hydrogen atom donation to carbon-centered radicals (157, 191). Although hydrogen atom transfer to carbon-centered radicals is a diffusion-controlled reaction, the extremely low concentrations of H2S and H2Sx in blood and tissues limit their efficiency at repairing free radical damage to biomolecules.