Fig. 4.
(A and B) fMRI activation maps showing selective FUS-mediated activation of the somatomotor area in the right cerebral hemisphere (visualized using a threshold of p<0.005). Spatial orientation is illustrated in the cartoon (inset). The crosshairs on the fMRI map indicate the location of the sonication focus. (C) FUS-mediated BOLD signal time course (percentage BOLD signal change) from the sonication focus (n = 4; with standard error) for two different acoustic intensities (3.3 and 6.4 W/cm2 Isppa). The BOLD signal from the unsonicated control site is shown in green line. The gray bar indicates the timing of the sonication.