Fig. 6.

(a–g) CTLm functional avidity. CTLm from each horse were stimulated for 7 days with the indicated peptides at 10 pM (0.00001 μM) to 100 μM and then added at an effector:target cell ratio of 20:1 to homologous EK targets pulsed with the same peptides at 10⁻¹-10⁵ nM. Functional avidity is the peptide concentration that results in 50% maximal target cell lysis and was not determined for CTLm stimulations resulting in maximum specific lysis less than 10% above the % specific lysis of homologous target cells not pulsed with peptide. Peptide concentrations used to stimulate each CTLm subline are shown in boxes.