Table 1.
Linear associations between 24-h blood pressure and urinary 15-keto-dihydro-PGF2α and serum IL-6, CRP and SAA in the study population.
| Inflammatory biomarkers, median [interquartile interval] | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 15-keto-dihydro-PGF2α 280 [213-374] (pmol/mmol Cr) | IL-6 2.8 [2.1-4.7] (ng/L) | CRP 1.8 [1.0-4.3] (mg/L) | SAA 4.0 [2.4-7.0] (mg/L) | ||||||||||
| r | P | P (adj.) | r | P | P (adj.) | r | P | P (adj.) | r | P | P (adj.) | ||
| Blood pressure (mmHg) mean ± SD (CV%) | 24-hour SBP 134 ± 15 (11) | -0.11 | <0.01 | <0.01 | -0.03 | 0.50 | 0.64 | 0.09 | <0.05 | 0.16 | 0.09 | <0.05 | 0.08 |
| Day-time SBP 138 ± 16 (12) | -0.10 | <0.05 | <0.05 | -0.05 | 0.90 | 0.89 | 0.07 | 0.07 | 0.29 | 0.08 | <0.05 | 0.14 | |
| 24-hour DBP 73 ± 8.1 (11) | -0.10 | <0.05 | <0.01 | -0.08 | <0.05 | <0.05 | -0.03 | 0.43 | 0.16 | -0.01 | 0.90 | 0.55 | |
| Day-time DBP 76 ± 8.6 (11) | -0.10 | <0.05 | <0.01 | -0.11 | <0.01 | <0.05 | -0.05 | 0.22 | 0.09 | -0.03 | 0.47 | 0.24 | |
| 24-hour PP 61 ± 12 (20) | -0.07 | 0.08 | 0.10 | 0.09 | <0.05 | <0.05 | 0.14 | <0.001 | <0.01 | 0.13 | <0.01 | <0.01 | |
Cr, urinary creatinine; SBP, systolic blood pressure; DBP, diastolic blood pressure; r, correlation coefficient; P, unadjusted p-value; P (adj.), linear regression model adjusting for antihypertensive treatment, history of cardiovascular diseases, smoking, diabetes, BMI and low-dose aspirin treatment; PP, pulse pressure.