Table 3.
The effect of Н202 on DCF mean fluorescence (Mean Flu) and the ratio of necrotic cells in populations of neurons isolated from cerebellum of pups subjected to prenatal hyperhomocysteinemia±pinealon (* – statistically significant difference from I, # – statistically significant difference from III)
| Animal group | Mean Flu, Arb.U. | % of PI labelled cells |
|---|---|---|
| I. Methionine loaded | 51.6±2.3 | 12.6±1.2 |
| II. “Methionine+pinealon” loaded | 54.2±2.8 | 3.4±0.7 |
| III. Methionine loaded + Н202 | 158.7±3.8 (*, p<0.01) | 17.7±2.1 (*, p<0.05) |
| IV. “Methionine+pinealon” loaded + Н202 | 108.6±4.1 (#, p<0.05) | 7.0±0.9 (#, p<0.05) |