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Nuclear HDAC7 is correlated with HIF-1α protein in nuclei in PBMC. PBMCs were incubated in the hypoxic chamber (1% oxygen, 5% CO2, and 94% N2) for 24 h and nuclear protein was extracted. A, HDAC7 protein level in nuclei corrected to the lamin A protein expression. B, HDAC7 protein levels correlated with HIF-1α protein expression. *P < .05. HDAC = histone deacetylase. See Figure 1 legend for expansion of other abbreviations.
