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. Author manuscript; available in PMC: 2012 May 3.
Published in final edited form as: Stat Appl Genet Mol Biol. 2012 Mar 31;11(3):10.1515/1544-6115.1750 /j/sagmb.2012.11.issue-3/1544-6115.1750/1544-6115.1750.xml. doi: 10.1515/1544-6115.1750

Figure 4. SES recovers SDS false negatives.

Figure 4

sp100 is expressed at 2.4 fold above the median expression level of all genes in NSC. Yet, under SDS the promoter region shows no statistically significant enrichment of H3K4me3 IP over Input, despite it being an epigenetic mark of active transcription. Under SES, the sp110 promoter region is detected as methylated. Note that p-values were not computed at positions where Input density exceeds IP density.