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KRAS genotype frequencies and histopathologic grade according to HRT stratification
| Study population | Genotype | Frequency | p value | |
|---|---|---|---|---|
| N(%) | ||||
| 1/2 | 3 | |||
| All | wild(TT) | 261(84.2) | 165(80.5) | 0.276 |
| variable(TG/GG) | 49(15.8) | 40(19.5) | ||
| Nonusers: HRT < 1 year | wild(TT) | 167(81.1) | 130(83.3) | 0.578 |
| variable(TG/GG) | 39(18.9) | 26(16.7) | ||
| Users: HRT 1 years | wild(TT) | 94(90.4) | 35(71.4) | 0.003 |
| variable(TG/GG) | 10(9.6) | 14 (28.6) | ||
Statistically significant results are shown in bold
