Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 May 3;8(5):e1002658. doi: 10.1371/journal.pgen.1002658

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Wollmann et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A–B) Average profile of H3.3 (green) and H3.1 (orange) enrichment over genes that are five fold up-regulated in dividing tissue (plain line) compared to non-dividing tissue (dashed line) (194 genes) (A) and vice versa (88 genes) (B). The average H3.3 enrichment varies during development and follows expression changes (A–B). In contrast, the average H3.1 enrichment does not vary significantly during the developmental transition (A–B). (C) Scatterplots of the modulation of H3.3 (green), H3.1 (orange), H3 (blue) and IgG (dashed grey) enrichment rank versus gene expression rank in dividing compared to non-dividing tissue. A sliding window of 500 genes was applied on both the gene expression difference and the differential enrichment. Only the modulation of H3.3 shows a positive correlation with changes of levels of expression.