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. Author manuscript; available in PMC: 2012 May 3.
Published in final edited form as: Cancer Biomark. 2010;6(1):33–48. doi: 10.3233/CBM-2009-0117

Fig. 2.

Fig. 2

Immunohistochemical staining for MRE11, Her2, and p53 in tissue sections obtained from a patient with serous high grade carcinoma. Immunohistochemical staining for RAD50 was performed in tissue sections obtained from a patient with mixed epithelial carcinoma. Although MRE11 and RAD50 were not previously identified as serological biomarkers, IHC was performed to determine their protein expression level because of their biological functions as stated earlier. Known prognostic markers Her2 and p53 were also included in this study. Nuclear staining was observed for MRE11 (A) and RAD50 (B), membranous staining was observed for Her2 (C), nuclear staining was observed for p53 (D). Magnification in all panels is X20.