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. 2012 Apr;19(4):339–353. doi: 10.1177/1933719111432867

Table 1.

GnRH, GnRH Agonists’ Relative Potency, Route of Administration, and the Dose Regimen2,51

Relative Potency Route of Administration Dose Regimen
GnRH 1
Leuprolide (Lupron) 15 Subcutaneous injection 500-1000 mg/d
Intranasal 400 mg _4 days
Intramuscular depot 3.75-7.5 mg/month
11.25 mg/3 months
Buserelin (Suprefact, CinnaFact) 20 Subcutaneous injection 200 mg/day
Intranasal 300-344 mg × 4 days
Nafarelin (Synarel) Intranasal 3 mg/month
Intramuscular depot depot 2-4 mg/month
Deslorelin (Ovuplant) 114
Histrelin (Vantas, Supprelin LA) 210 Subcutaneous injection 100 mg/day
Goserelin (Zoladex) Subcutaneous implant 3.6 mg/month
10.8 mg/3 months
Tryptorelin (Decapeptyl, Diphereline, Gonapeptyl, Trelstar) Intramuscular depot 3 mg/month