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. 2012 May;19(5):483–492. doi: 10.1177/1933719111432870

Figure 3.

Figure 3.

Gene expression levels of histone deacetylase (HDAC) 1/2 in endometrial and endometriotic tissues. A, Relative gene expression levels in tissues: RNA was isolated from flash-frozen tissues and quantitative polymerase chain reaction (qPCR) was conducted using TaqMan assays. Results are expressed as relative units (RU) after normalization with the reference gene glyceraldehyde 3-phosphate dehydrogenase (GAPDH). The HDAC1 was expressed in tissues of patients with endometriosis (endometriotic and eutopic endometrium), and in the endometria of patients with fibroids. The highest mean expression of HDAC1 was observed in the endometria of patients with endometriosis. Similar results were observed for HDAC2, which was expressed in a substantial proportion of tissues from patients with endometriosis and fibroids. The highest expression of HDAC2 was in endometria from patients with endometriosis. B, Correlations of HDAC1/2 gene expression levels in tissues: a positive and significant correlation was observed in the levels of HDAC1/2 only in endometriotic lesions.