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Protein solubilities (liquidus lines). (a) The solubility lines of HGD (open diamonds), R58H (circles), and R36S (squares) are shown together with the liquid–liquid coexistence curve of HGD (crossed diamonds). (b) Logarithmic-linear plot of the data in a was used to extract the enthalpies and entropies of the protein crystals. The lines are fits to Eq. 1. T0 is a reference temperature that was taken to be 298 K.
