Gd3+, La3+, and low-dose Ni2+ inhibit 5-hydroxytryptamine (5-HT)-elicited contraction. Bars indicate mean ± SEM of %T5-HT Control for the noted condition in pulmonary arterial rings from normoxic (open) or LTH (solid) fetal sheep. *P < .05, **P < .01, and ***P < .001 denote significant difference based on a 2-way ANOVA and a Bonferroni post hoc analysis. LTH indicates long-term hypoxia; SEM, standard error of the mean; ANOVA, analysis of variance.