Table 3.

Comparison For Hardy–Weinberg Equilibrium in COMT Gene in Caucasian and African American Women That Delivered Preterm (Cases) and Term (Controls)^a

		Caucasians				African Americans
SNP	MA	Cases		Controls		Cases		Controls
		n	MAF	n	MAF	n	MAF	n	MAF
Maternal COMT gene
RS6269	G	68	0.456	188	0.414	41	0.317	223	0.346
RS4633	T	68	0.455	188	0.489	41	0.375	223	0.346
RS4818	G	68	0.463	188	0.411	41	0.171	223	0.220
RS4680	A	68	0.455	188	0.487	41	0.293	223	0.287
Fetal COMT gene
RS6269	G	70	0.343	196	0.408	35	0.286	219	0.393
RS4633	C	70	0.443	197	0.500	35	0.371	217	0.300
RS4818	G	70	0.314	193	0.391	35	0.086	221	0.251
RS4680	G	70	0.450	195	0.490	35	0.357	217	0.288

Abbreviations: COMT, catechol-O-methyltransferase; SNP, single-nucleotide polymorphism; MA, minor allele; MAF, minor allele frequency.

^aSignificance by Fisher exact test.