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. 2011 Feb;18(2):128–135. doi: 10.1177/1933719110381923

Figure 2.

Figure 2.

Spheroids form vesicle structures. Spheroids were formed in nonadherent bioreactors for 7 to 10 days. They were removed from the bioreactor, fixed, sectioned, and stained with hematoxylin and eosin (H&E; a). The hollow structure is confirmed by confocal microscopy through the edge (b) and center (c) of the spheroid.