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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: J Invest Dermatol. 2012 Feb 2;132(7):1869–1876. doi: 10.1038/jid.2011.463

Figure 2. T cells accumulate in the skin during vitiligo.

Figure 2

(a) GFP-labeled CD8+ T cells were quantified by flow cytometry of ear skin at the indicated times (error bars = mean +/− SEM, n=3 per time point). Example flow plots of the CD45+ gate are shown. (b) Tail skin from affected mice harvested 5 wks after transfer (mouse) is shown with affected skin from a vitiligo patient (human), revealing a patchy mononuclear infiltrate at the dermal-epidermal junction and epidermal infiltration (arrows). Normal mouse skin is shown at inset, scale bars=50μm. (c) Ears were harvested from mice with vitiligo at 5 wks after induction and GFP+ T cells were visualized with fluorescent microscopy (arrow). Scale bars=100μm. Hairs are visible as short, linear yellow structures due to autofluorescence.