Table I.
Demographic and clinical characteristics of the cases and controls at the time of the index visit.
| Characteristic | Cases | Controls | p-value |
|---|---|---|---|
| Number of patients | 20 | 20 | - |
| Male sex, No. | 8 | 8 | - |
| Caucasian ethnicity, No. | 17 | 19 | 0.16 |
| Age in years at CF diagnosis, median (range) |
0.74 (0–6.58) |
1.74 (0–9.41) |
0.11 |
| F508del mutations, No.: | |||
| ○ One | 12 | 11 | |
| ○ Two | 4 | 6 | 0.83 |
| Pancreatic insufficient, No. | 20 | 20 | - |
| History of airway infection, No.: | |||
| ○ Pseudomonas aeruginosa | 18 | 13 | 0.10 |
| ○ Burkholderia cepacia | 2 | 0 | 0.16 |
| ○ Methicillin-resistant Staphylococcus aureus | 4 | 7 | 0.32 |
| CF-related diabetes, No. | 2 | 2 | 0.99 |
| CF-related liver disease, No. | 3 | 1 | 0.32 |
| At the index visit, mean±SD: | |||
| ○ Age in years | 9.0±4.4 | 9.1±4.7 | 0.54 |
| ○ Height Z-score | −0.94±0.50 | −0.51±1.06 | 0.10 |
| ○ Weight Z-score | −1.40±0.55 | −1.06±0.74 | 0.07 |
| ○ BMI Z-score | −1.19±0.60 | −1.10±0.50 | 0.10 |
| ○ FEV1 percent predicteda | 76.0±19.5 | 75.7±19.0 | 0.90 |
a
Data available for 14 cases and 13 controls