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. 2012 Feb 29;81(10):1002–1014. doi: 10.1038/ki.2011.457

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Copyright © 2012 International Society of Nephrology

This work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Albuminuria and renal histology in BMT uninephrectomized mice at 16 weeks of dietary intervention. (a) Representative western blot analyses of SR-A expression in circulating leukocytes. (b) Urinary albumin/creatinine. (c) Representative histological photomicrograph of kidney stained for glomerular mesangial matrix (periodic acid–Schiff stain). Scale bar=19 μm. (d) Bar graph summarizing the mesangial matrix index (MMI) in periodic acid–Schiff–stained section. (e) Bar graph summarizing the percentage of tubulointerstitial fibrosis area in trichrome-stained section. Each bar represents the mean±s.e.m. for at least six mice. BMT, bone marrow transplantation; SR-A, scavenger receptor A; SR-A^+/+, SR-A wild-type mice; SR-A^−/−, SR-A deficiency mice.