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. 2012 Feb 29;81(10):1002–1014. doi: 10.1038/ki.2011.457

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Copyright © 2012 International Society of Nephrology

This work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Renal lipid accumulation, leukocyte filtration, and cytokine expression in BMT uninephrectomized mice at 16 weeks of dietary intervention. (a) Renal cholesterol content in the kidney. Percentage of (b) CD11c⁺ and (c) CD68⁺ cells in the kidneys analyzed by flow cytometry. (d) Renal cytosolic MCP-1, (e) TNF-α, and (f) IL-6 assayed by enzyme-linked immunosorbent assay. Each bar represented the mean±s.e.m. for at least six mice. BMT, bone marrow transplantation; IL-6, interleukin-6; MCP-1, monocyte chemoattractant protein-1; SR-A, scavenger receptor A; SR-A^+/+, SR-A wild-type mice; SR-A^−/−, SR-A deficiency mice; TNF-α, tumor necrosis factor-α.