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. 2012 Feb 29;81(10):1002–1014. doi: 10.1038/ki.2011.457

Table 3. Metabolic data of the BMT mice at 16 weeks of dietary intervention.

  Normal diet
High-fat diet
Groups WT to WT (n=6) WT to SR-A−/− (n=6) SR-A −/− to WT (n=7) WT to WT (n=6) WT to SR-A−/− (n=6) SR-A −/− to WT (n=5)
Body weight (g) 33.4±3.5 34.2±2.5 34.1±2.5 54.9±3.6a 55.5±3.4b 55.3±4.7c
BP (mm Hg) 92.5±10.3 92.7±9.3 92.0±11.5 92.2±10.7 94.2±10.8 93.1±8.9
Plasma Cr (mol/l) 62.5±5.3 66.5±6.4 63.5±4.7 110.4±6.5a 106.0±7.8b 96.2±8.5c,d,e
Plasma triglyceride (mmol/l) 1.33±0.56 1.41±0.61 1.35±0.36 2.55±0.41a 2.58±0.63b 2.54±0.94c
Plasma cholesterol (mmol/l) 2.45±0.48 2.39±0.63 2.49±0.46 6.76±0.93a 6.79±0.69b 6.72±0.76c
Plasma MCP-1 (μg/l) 129.1±9.2 126.1±8.7 128.9±9.7 279.0±10.2a 264.0±11.2b 167.0±10.3c,d,e
Plasma IL-6 (μg/l) 112.5±6.7 108.3±6.9 110.4±6.3 469.9±8.7a 439.1±14.6b 211.2±9.5c,d,e
Plasma TNF-α (μg/l) 73.5±6.9 69.0±7.8 68.5±7.1 159.9±6.8a 174.6±10.1b 99.20±14.6c,d,e

Abbreviations: BMT, bone marrow transplantation; BP, blood pressure; Cr, creatinine; IL-6, interleukin-6; MCP-1, monocyte chemoattractant protein-1; SR-A, scavenger receptor A; SR-A−/−, SR-A deficiency mice; TNF-α, tumor necrosis factor-α WT, SR-A wild-type mice.

a

P<0.05 versus WT to WT BMT mice fed with normal diet.

b

P<0.05 versus WT to SR-A−/− BMT mice fed with normal diet.

c

P<0.05 versus SR-A−/− to WT BMT mice fed with normal diet.

d

P<0.05 versus WT to WT BMT mice fed with high fat diet.

e

P<0.05 versus WT to SR-A−/− BMT mice fed with high-fat diet.

Data are means±s.e.m.