Table 2.
Transcriptional changes induced by hyperosmolar stress in selected homeostatic genes
Functional Group |
Ratio of expression; 24hr stress/T0 (unstressed) | ||||
---|---|---|---|---|---|
Genes | 0hr (Arbitrary units) |
24hr | T24/T0 | P | Accession number |
CDKI p15 p21 |
118 268 |
283 1443 |
2.4 5.4 |
0.004 0.03 |
AF059567 AK007630 |
GADD45 and DDIT GADD45β GADD45γ DDIT3(CHOP10) DDIT4 |
341 133 100 484 |
1614 1687 529 1133 |
4.7 12.7 5.3 2.3 |
0.002 0.007 0.0004 0.022 |
AI323528 AK007410 NM_007837 AK017926 |
HSP HSP22/Hspb8 HSP68/Hspa1a HSP70.1/Hspa1b HSP70.2/Hspa2 |
325 479 100 100 |
1079 2142 518 208 |
3.3 4.5 5.2 2.1 |
0.033 5.81E-05 0.01 0.0003 |
AF250139 AW763765 M12573 BC004714 |
AP1 JunC ATF3 ATF4 |
210 159 822 |
1243 736 1561 |
5.9 4.6 1.9 |
0.04 0.019 0.023 |
NM_010591 BC019946 M94087 |
Msx2/Hox8 280 | 949 3.4 | 0.03 | NM_010261 |