Table 4.
Lack of significant transcriptional changes induced by sorbitol are detected for some markers of pluripotent TSC, primary and secondary TGC, spongiotrophoblasts, and syncytiotrophoblasts.”
|
Functional Group |
Ratio of expression; 24hr stress/T0 (unstressed) | ||||
|---|---|---|---|---|---|
| Genes | 0hr (Arbitrary units) |
24hr | T24/T0 (%) |
P value |
Accession number |
| TSC | |||||
| Cdx2 | 630 | 359 | 0.6 | 1 | NM_007673 |
| Eomesodermin | 1218 | 649 | 0.5 | 1 | BB128925 |
| ErrBeta | 478 | 226 | 0.5 | 0.22 | BB386239 |
| Cyclin A2 | 1200 | 714 | 0.6 | 1 | X75483 |
| Cyclin B1 | 2159 | 1351 | 0.6 | 0.68 | AU015121 |
| Eed | 905 | 965 | 1.1 | 1 | U97675 |
| Id1 | 244 | 285 | 1.2 | 1 | U43884 |
| Id2 | 2604 | 2401 | 0.9 | 1 | NM_010496 |
| AP2y | 1676 | 1576 | 0.9 | 1 | BB550860 |
| Cyclin D3 | 749 | 607 | 0.8 | 0.08 | NM_007632 |
| TGC primary | |||||
| HAND1 | 1607 | 1581 | 1.0 | 1 | U43714 |
| PL1 | 100 | 160 | 1.6 | 1 | BB414739 |
| TGC secondary | |||||
| PL-II | 100 | 100 | 1.0 | 1 | NM_008865 |
| PLP-A | 100 | 100 | 1.0 | 1 | |
| Spongiotropoblast | |||||
| MASH2 | 100 | 100 | 1.0 | 1 | NM_008554 |
| TPBPa/4311 | 100 | 100 | 1.0 | 1 | NM_009411 |
| Flt1 | 117 | 307 | 2.6 | 0.16 | D88690 |
| Placenta specific 8 | 131 | 473 | 3.6 | 0.15 | AF263458 |
| Svncvtiotrophoblast | |||||
| GCM1 | 100 | 100 | 1.0 | 1 | NM_008103 |
| TEF5 | 100 | 100 | 1.0 | 1 | NM_011566 |
| CXCR4 | 100 | 166 | 1.7 | 1 | D87747 |
| Dlx3 | 100 | 100 | 1.0 | 1 | U79738 |