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. 2012 May 4;2:396. doi: 10.1038/srep00396

Figure 1. The targeting procedure.

Figure 1

The MN and SN are initially disconnected. Each targeting step establishes a new unidirectional connection between both networks. At the current step, a subgraph of the MN is connected to its counterpart in the SN (see gray continuous line). The searching step establishes a further connection via that node (see gray dotted line) that minimizes the associated MSF.