Table 2. Analyses of plasma and urine electrolytes in WT and CLDN14 KO mice under high Ca++ dietary condition.
WT | CLDN14 KO | Significance | |
---|---|---|---|
Weight, g | 19.04±0.58 | 19.36±2.56 | n.s. |
PCa, mM | 2.74±0.02 | 2.75±0.05 | n.s. |
PMg, mM | 0.93±0.03 | 1.07±0.03 | P<0.05 |
UV, μl/24 h/g | 45.58±7.09 | 40.82±13.32 | n.s. |
GFR, ml/24 h/g | 3.91±0.21 | 7.20±0.56 | P<0.01 |
FECa, % | 1.65±0.08 | 0.53±0.15 | P<0.01 |
FEMg, % | 7.03±1.00 | 3.14±0.44 | P<0.05 |
FECa, FEMg, fractional excretion of Ca++ and Mg++; GFR, glomerular filtration rate; n.s., not significant; PCa, PMg, plasma Ca++ and Mg++ concentrations; UV, urine volume. | |||
Values are expressed as means±s.e.m.; n=6, the number of animals; sex, male; age, 9–10 weeks. |