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. Author manuscript; available in PMC: 2012 May 4.
Published in final edited form as: J Mol Biol. 2009 Jul 30;393(2):383–396. doi: 10.1016/j.jmb.2009.07.077

Figure 2.

Figure 2

Circular dichroism spectra of IAPP. (a) Far UV-CD of rIAPPred (green), rIAPP (black) and hIAPP (blue) in 0% and 40% TFE. (b) Mean molar residue ellipticity (MRE) at 222 nm is plotted against TFE % for each IAPP variant. Average values from experiments done in triplicate are plotted as points with error bars as one standard deviation. Data were fit to a two-state model and plotted as solid lines. (c) Far UV-CD spectra recorded at 30°C of 40 μM rIAPP (black) and hIAPP (blue) in standard conditions and with 20 mM bicelles (red and grey, respectively).