Table 5.
Multivariate model of predictors of multiple organ failure
| Hazard Ratio | 95% C.I. | P | |
|---|---|---|---|
| Demographics | |||
| Male gender | 2.19 | 1.51 – 3.18 | <0.0001 |
| Comorbidity | |||
| Hypertension | 2.10 | 1.34 – 3.29 | 0.0011 |
| Liver disease | 2.29 | 1.08 – 4.845 | 0.03 |
| Injury Characteristics | |||
| AIS ≥3 | |||
| Thorax | 1.67 | 1.13 – 2.46 | 0.01 |
| Extremity | 1.72 | 1.19 – 2.48 | 0.004 |
| APACHE II (per point) | 1.06 | 1.03 – 1.09 | 0.0002 |
| ISS | 1.01 | 0.99 – 1.03 | 0.075 |
| Resuscitation Parameters | |||
| Crystalloid 12-24 hours, L (per liter) | 1.09 | 1.03 – 1.15 | 0.003 |
| FFP 1st 12 hours, L (per liter) | 1.31 | 1.15 – 1.51 | <0.0001 |
| Vasopressor use | 2.09 | 1.51 – 3.18 | 0.0004 |
| Physiologic Parameters | |||
| Worst BD 12-24 hours | 0.95 | 0.91 – 0.99 | 0.02 |
| Worst lactate 1st 12 hours | 1.07 | 1.01 – 1.14 | 0.04 |
AIS: Abbreviated injury score; FFP: Fresh frozen plasma; BD: base deficit; CI: confidence interval; APACHE: Acute physiology and chronic health evaluation