Table 4.

Creatinine Clearance and Proteinuria After Weekly i.v. Administration (40 mg Iron/kg Body Weight or Equivalent Volume) in the ISS, IS_ORIG and Control Groups Over a 4-Week Period

Day	ISSFERP (n = 10)	ISSFERI (n = 10)	ISSFERO (n = 10)	ISSENCI (n = 10)	ISSBACK (n = 10)	ISSLIB (n = 10)	ISORIG (n = 10)	Control (n = 10)
CrCl
1	2.4 ± 0.1	2.3 ± 0.1	2.4 ± 0.2	2.1 ± 0.1	2.2 ± 0.1	2.3 ± 0.2	2.7 ± 0.1#	2.8 ± 0.1*
8	3.3 ± 0.1	2.2 ± 0.1	2.3 ± 0.1	2.2 ± 0.2	2.3 ± 0.2	2.3 ± 0.1	2.8 ± 0.1#	2.9 ± 0.1#
29	2.1 ± 0.1	2.2 ± 0.1	2.2 ± 0.1	2.3 ± 0.2	2.1 ± 0.2	2.4 ± 0.2	2.7 ± 0.1#	2.9 ± 0.1#
Proteinuria
1	19.2 ± 5.5	22.1 ± 6.2	16.9 ± 7.1	18.5 ± 7.9	17.4 ± 5.8	19.9 ± 5.8	2.0 ± 1.3#	1.2 ± 2.0#
8	21.9 ± 6.6	26.3 ± 7.7	27.3 ± 9.9	33.2 ± 5.8	22.9 ± 4.9	25.1 ± 4.1	5.7 ± 2.4#	4.1 ± 2.1#
29	35.4 ± 7.0	31.8 ± 8.2	30.7 ± 5.9	39.4 ± 8.2	35.1 ± 5.8	29.8 ± 7.9	6.3 ± 3.0#	3.8 ± 3.0#

^*p< 0.01 versus all groups

^#p< 0.01 versus ISS_FERP, ISS_FERI, ISS_FERO, ISS_ENCI, ISS_BACK, ISS_LIB