Table 5.
Prussian Blue Staining and Ferritin Immunostaining in the Liver, Heart and Kidney Samples of the Six Asian ISS Groups, the ISORIG Group, and the Control Group on Day 29
| Mean ± SD | ISSFERP (n = 10) | ISSFERI (n = 10) | ISSFERO (n = 10) | ISSENCI (n = 10) | ISSBACK (n = 10) | ISSLIB (n = 10) | ISORIG (n = 10) | Control (n = 10) |
|---|---|---|---|---|---|---|---|---|
| Prussian blue (% positive staining/area) | ||||||||
| Liver | 6.8 ± 2.0 | 15.1 ± 3.2 | 14.6 ± 2.2 | 14.2 ± 2.6 | 14.7 ± 2.8 | 14.9 ± 1.8 | 7.4 ± 2.0# | 1.2 ± 0.5* |
| Heart | 4.1 ± 0.7 | 3.8 ± 0.6 | 4.0 ± 0.7 | 3.6 ± 0.8 | 3.9 ± 0.7 | 3.7 ± 0.8 | 1.1 ± 0.3# | 0.2 ± 0.1* |
| Kidney | 7.1 ± 1.0 | 6.2 ± 1.2 | 6.6 ± 1.5 | 6.4 ± 1.8 | 6.8 ± 1.3 | 6.3 ± 1.4 | 3.1 ± 0.8# | 1.3 ± 0.1* |
| Ferritin (% positive staining/area) | ||||||||
| Liver | 7.3 ± 2.0 | 6.9 ± 1.7 | 6.8 ± 1.4 | 7.5 ± 2.0 | 7.5 ± 1.1 | 7.1 ± 2.0 | 15.2 ± 1.4# | 2.1 ± 0.6* |
| Heart | 1.8 ± 0.4 | 1.7 ± 0.3 | 1.9 ± 0.4 | 1.7 ± 0.5 | 1.4 ± 0.5 | 1.6 ± 0.6 | 3.1 ± 0.4# | 0.2 ± 0.1* |
| Kidney | 3.6 ± 0.5 | 3.0 ± 0.5 | 2.7 ± 0.7 | 3.3 ± 0.5 | 3.6 ± 0.3 | 3.4 ± 0.6 | 6.1 ± 0.7# | 0.2 ± 0.1* |
*
p < 0.01 versus all groups
#
p < 0.01 versus ISSFERP, ISSFERI, ISSFERO, ISSENCI, ISSBACK, ISSLIB