Figure 2.
The caspase-3 proenzyme exhibits catalytic activity in apoptotic Jurkat cell extracts. (a) Caspase-3 proenzyme organization. (b) Structure of the active-site probe, biotin-DEVD-aomk (L772,094). (c) Biotinylation of procaspase-3 by L772,094 in apoptotic extracts from Jurkat cells. I, α-caspase-3 immune; PI, preimmune.