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Binding of ATP to the P2X and P2Y series of receptors. ADP preferentially binds to the P2Y series of receptors. CD39 is involved in the catabolism of ATP to ADP to AMP. CD73 is involved in the catabolism of AMP to ADO. ADO preferentially binds to the P1 series of receptors. CD26 in association with adenosine deaminase metabolizes ADO to inosine which is further reduced by xanthine oxidase to uric acid.
