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Urinary HIF-1alpha levels in patients with lupus nephritis and in healthy controls. Urinary HIF-1alpha levels were significantly higher in patients with lupus nephritis than in healthy controls (3.977±1.696 vs. 2.153±0.554 ng/mL, p<0.001). The bars indicate group mean values (A). Urinary HIF-1alpha levels were associated with histologic chronicity indices (r=0.463, p<0.01) (B) and eGFR (r=-0.324, p<0.05) (C). HIF, hypoxia-inducible transchiption factor.
