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. 2001 May 8;98(11):6144–6149. doi: 10.1073/pnas.101596998

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Copyright © 2001, The National Academy of Sciences

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Genetic interactions between dPDK-1 and Drosophila PI3K in cell size control. Microscopic views of the wings expressing ptc-GAL4/UAS-PI3KDN (A), ptc-GAL4/UAS-PI3KDN; EP(3)3553/+ (B), ptc-GAL4/UAS-PI3K (C), and ptc-GAL4/UAS-PI3K; EP(3)3553/+ (D). The relative distances between two arrows are ptc-GAL4/UAS-PI3KDN (58%), ptc-GAL4/UAS-PI3KDN; EP(3)3553/+ (100%), ptc-GAL4/UAS-PI3K (125%), and ptc-GAL4/UAS-PI3K; EP(3)3553/+ (142%), respectively. Increased activities of the PI3K signaling pathway induced a loss of cross-veins (B and D), as reported (45).