Characteristic	Resistant N=2,521	Non-Resistant N=15,515	p-value
Gender			<0.01
Male	49.8%	44.4%
Race			<0.01
Black	8.1%	8.7%
Missing	14.2%	13.8%
Other	19.0%	23.6%
White	58.7%	53.9%
Age*	57.8 (57.4–58.3)	56.6 (56.4–56.8)	<0.01
Baseline Systolic BP*	153.8 (153.1–154.5)	145.1 (144.9–145.4)	<0.01
Baseline Diastolic BP*	85.7 (85.2–86.2)	83.5 (83.3–83.7)	<0.01
Body Mass Index*	31.5 (31.2–31.9)	30.3 (30.0–30.6)	<0.01
Current smoker
Yes	10.9%	10.1%	0.21
Site			0.04
Kaiser Northern California	95.7%	96.6%
Kaiser Colorado	4.3%	3.4%
Year of hypertension registry entry			<0.01
2000	2.7%	2.1%
2001	15.7%	17.0%
2002	37.8%	33.5%
2003	20.5%	21.5%
2004	11.9%	13.3%
2005	6.9%	8.2%
2006	4.5%	4.4%
Baseline co-morbidities
Albuminuria	0.3%	0.2%	0.27
Alcohol abuse	4.0%	3.4%	0.13
Angina	0.5%	0.6%	0.69
Asthma	9.2%	12.5%	<0.01
Atrial fibrillation	1.9%	1.1%	<0.01
Bipolar	0.8%	0.8%	0.86
Diabetes	16.4%	8.2%	<0.01
Depression	9.8%	14.0%	<0.01
Drug abuse	9.8%	14.0%	<0.01
Peripheral Vascular Disease	0.8%	0.8%	0.81
Sleep apnea	2.2%	2.2%	0.85
Baseline Hypertension Medications
Beta Blockers	77.7%	65.4%	<0.01
ACE/ARB	67.9%	68.6%	0.43
All Diuretics	93.1%	93.3%	0.66
K-sparing Diuretics	36.7%	38.2%	0.16
Calcium Channel Blocker	28.0%	22.6%	<0.01
Alpha Adrenergic Blocker	8.2%	6.7%	<0.01
Peripheral Vasodilators	0.6%	0.3%	0.05

^*Continuous variables are presented as mean and 95% confidence interval.