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. Author manuscript; available in PMC: 2012 May 4.
Published in final edited form as: Transplant Proc. 2009 Jul-Aug;41(6):2601–2606. doi: 10.1016/j.transproceed.2009.06.025

Figure 1.

Figure 1

Increased expression of KCa3.1 and Kv1.3 channels in LEW T-lymphocytes after MLR (stimulated for 4 days with irradiated F344 splenocytes). (A) Representative traces of Kv1.3 and KCa3.1 currents in unstimulated LEW rat T-cells (upper panel) and after allogeneic stimulation (lower panel). Voltage-dependent Kv1.3 currents were sensitive to ShK and the voltage-independent KCa3.1 current component was sensitive to the selective KCa3.1 blocker TRAM-34. (B) Quantification of KCa3.1 and Kv1.3 channel numbers per cell in stimulated and unstimulated T-cells. Data are given as mean ± SEM.