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. Author manuscript; available in PMC: 2013 Apr 15.
Published in final edited form as: J Immunol. 2012 Mar 9;188(8):3876–3885. doi: 10.4049/jimmunol.1103024

Figure 6. CCL2 induced IFNα suppression occurs through CCR2 signaling.

Figure 6

(A–B) SIV infected primary MDM were treated with either propagermanium (prop), CCL2 (CCL2), CCL2 + propagermanium (CCL2 + prop), or left untreated (UT). Cells were harvested 48 hours p.i. and RNA was isolated. qRT-PCR analysis was done for (A) IFNα or (B) IFNβ. Data represents means of 3 independent experiments (each done with 2 technical replicates) with 95% confidence interval. One-way ANOVA with Bonferroni post test for multiple comparisons was performed on the SIV infected group, and selected pairwise comparisons are shown. Results were considered significant with p<0.05.