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. 2001 May 8;98(11):6168–6173. doi: 10.1073/pnas.111027698

Figure 3.

Figure 3

Role of MAPK in apoptosis and expression of MAO. Neuronal PC12 cells were incubated in the presence and absence of NGF (24 h). (A) Apoptosis was measured with a nucleosomal DNA fragmentation assay (mean ± SD; n = 3). The effect of treatment of the cells with inhibitors of p38 MAPK (PD169316) and the extracellular signal-regulated kinase pathway (PD98059) was examined. Similar data were obtained in three independent experiments. (B) MAO A and β-actin mRNA expression was examined by Northern blot analysis. The effect of treatment with the p38 inhibitor PD169316 is presented. Similar data were obtained in three independent experiments.