Table 2.
Homozygous wild-type | Homozygous mutant | P | Heterozygous mutant | P | Or (95% ci) mutant | Or (95% ci) hetero | |
---|---|---|---|---|---|---|---|
Leu1007fsinsC | |||||||
Patients | 7 (15.2%) | 3 (6.5%) | 0.012 * | 36 (78.3%) | <0.0001 * | 5.29 (2.71–10.29) | 7.71 (2.87–20.71) |
Controls | 30 (60.0%) | 0 (0.0%) | 20 (20.0%) | ||||
Arg702Trp | |||||||
Patients | 8 (17.4%) | 10 (21.7%) | <0.0001 * | 28 (60.6%) | <0.0001 * | 21.87 (3.99–119.9) | 9.42 (3.43–25.9) |
Controls | 35 (70.0%) | 2 (4.0%) | 13 (26.0%) | ||||
Gly908Arg | |||||||
Patients | 5 (10.9%) | 3 (6.5%) | 0.015 * | 38 (82.6%) | <0.0001 * | 21.0 (1.81–243.2) | 19.0 (6.20–58.21) |
Controls | 35 (70.0%) | 1 (2.0%) | 14 (28.0%) |
Statistically significant at P ≤ 0.05.