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. 2001 May 15;98(11):6204–6208. doi: 10.1073/pnas.111158298

Figure 5.

Figure 5

Summary of Giant interactions. (A) Diagram of a cellularizing embryo showing the normal giant expression pattern (Gt) in anterior and posterior regions. The posterior pattern represses the eve stripe 5 enhancer (St5) to establish the posterior stripe border. It is possible that Giant interacts with an unknown bZIP subunit, X, that is distributed throughout the region where stripe 5 is expressed. (B) Giant might recruit an unknown corepressor, “?”, via the VLDLS motif. It is possible that Giant also weekly interacts with dCtBP. The putative X subunit might strongly interact with dCtBP, so that mutations in the Giant repression domain do not impair the activity of Giant-X heterodimeric complexes.