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. 2012 Mar 6;9:46. doi: 10.1186/1742-2094-9-46

Figure 3.

Figure 3

Declined neurologic deficits and inflammation in MyD88 −/− and TRIF−/− mice. Compared to WT mice, both MyD88−/− and TRIF−/− mice had decreased brain water content (A), NDS (B), (C) Both MyD88−/− and TRIF−/− mice showed decreased protein levels of IL-6, TNF-α, and IL-1β, and (D) immunohistochemistry of CD68 showed decreased macrophage infiltration in the perihematoma region of MyD88−/− and TRIF−/− brain on day3 post-ICH. **P < 0.01 vs. sham group; ##P < 0. 01 vs. WT group. $$P < 0.01 vs. WT group, Bar = 50 μM in D. Values (mean ± SD, n = 3 for each group) are representative of three independent experiments.