Table 1. Features of mRNA grouped in translation classes.
| NIH3T3 | |||||
| Translation class | |||||
| Total | High | Low | Resistant | Inducible | |
| number of mRNAs* | 8159 | 317 | 383 | 276 | 599 |
| CDS length (nts) | 1257 | 801 | 939 | 1506 | 2241 |
| CDS G+C (%) | 53,1 | 53,96 | 51,54 | 53,33 | 48,59 |
| RnnAUG frequency | 0,87 | 0,91 | 0,86 | 0,89 | 0,84 |
| 5′ UTR length (nts) | 144 | 105 | 133 | 191 | 206 |
| 5′UTR G+C (%) | 65,31 | 64,14 | 61,66 | 61,49 | 61,48 |
| 3′UTR length (nts) | 804 | 298 | 586 | 973 | 1529 |
| 3′ UTR G+C (%) | 43,95 | 45,2 | 39,46 | 45,26 | 38,85 |
| uAUG≥1 (%) | 43,28 | 19,56 | 51,17 | 38,08 | 58,93 |
| uAUG≥2 (%) | 22,36 | 7,26 | 29,5 | 19,6 | 36,4 |
| uAUG ≥3 (%) | 13,3 | 4,11 | 18,75 | 12,35 | 24,05 |
| uAUG≥4 (%) | 7,88 | 1,9 | 11,96 | 6,92 | 15,32 |
| uAUG≥5 (%) | 4,77 | 1,9 | 8,87 | 4,75 | 10,14 |
| Jurkat | |||||
| Translation class | |||||
| Total | High | Low | Resistant | Inducible | |
| number of mRNAs* | 10303 | 524 | 426 | 1330 | 166 |
| CDS length (nts) | 1317 | 1055 | 891 | 1968 | 2225 |
| CDS G+C (%) | 53,8 | 46,64 | 56,46 | 47,96 | 48,51 |
| RnnAUG frequency | 0,86 | 0,87 | 0,88 | 0,86 | 0,84 |
| 5′ UTR length (nts) | 174 | 188 | 127 | 227 | 178 |
| 5′UTR G+C (%) | 66,51 | 68,12 | 63,29 | 65,19 | 60,53 |
| 3′UTR length (nts) | 847 | 1222 | 352 | 1703 | 697 |
| 3′ UTR G+C (%) | 41,98 | 35,34 | 42,55 | 38,03 | 40,71 |
| uAUG≥1 (%) | 48,96 | 45,6 | 43,9 | 58,12 | 41,57 |
| uAUG≥2 (%) | 27,07 | 23,65 | 23,24 | 34,74 | 25,3 |
| uAUG≥3 (%) | 16,74 | 15,25 | 15,05 | 22,26 | 18,07 |
| uAUG≥4 (%) | 10,54 | 10,68 | 12,2 | 15,94 | 13,86 |
| uAUG≥5 (%) | 7,06 | 6,48 | 8,44 | 10,38 | 7,23 |
*
Only mRNAs with A values ≥5.5+5′ UTR≥10+3′ UTR≥10 were selected for the analysis.
High = log2P/FM≥2. Low = log2P/FM≤−1,5. For rows 2, 5 an 7, values are medians. For the rest, values are expressed in % or frequency. Highly significant differences in the t-test are marked in bold (p<0.005).