Table 1. Association of nuclear SNPs with growth traits1 using family-based association analysis2.
SNP | Weight2 | Weight3 | Weight4 | |||||||||
by.x | t | P | Pempirical | by.x | t | P | Pempirical | by.x | t | P | Pempirical | |
nuSNP1 | −10.3 | −3.3 | 0.00096** | 0.096 | −25.6 | −2.8 | 0.00431** | 0.112 | −48.8 | −2.6 | 0.00782** | 0.084 |
nuSNP7 | 30.6 | 3.5 | 0.00049** | 0.075 | 83.6 | 3.2 | 0.00124** | 0.082 | 144.8 | 2.8 | 0.00468** | 0.07 |
nuSNP9 | −12.8 | −2.6 | 0.00781** | 0.141 | −24.8 | −1.8 | 0.06913 | 0.272 | −119 | −4.3 | 1.52e−05** | 0.002* |
nuSNP17 | 10.8 | 3.1 | 0.00179** | 0.136 | 27.5 | 2.8 | 0.00517** | 0.133 | 47.5 | 2.3 | 0.02046* | 0.152 |
nuSNP22 | −15.4 | −3.7 | 0.00022** | 0.058 | −32.9 | −2.7 | 0.00581** | 0.116 | −54.4 | −2.2 | 0.02665* | 0.144 |
nuSNP23 | −16.9 | −4.2 | 0.995e−05** | 0.032* | −38.4 | −3.3 | 0.00078** | 0.059 | −58.1 | −2.3 | 0.01821* | 0.126 |
nuSNP24 | −15.7 | −3.7 | 0.00018** | 0.051 | −33.1 | −2.7 | 0.00576** | 0.112 | −54.4 | −2.2 | 0.02721* | 0.147 |
nuSNP25 | 9.4 | 2.6 | 0.00775** | 0.221 | 22.2 | 2.1 | 0.03076* | 0.258 | 61.2 | 2.7 | 0.00566** | 0.088 |
Body weight was recorded on each animal at approximately 7 (Weight2), 9 (Weight3) and 12 (Weight4) months post-hatching.
Family-based association analysis was performed with program PLINK version 1.07 [22]. Here, t is the t-statistic for regression of phenotype on allele count (by.x), P is the asymptotic P-value for t-statistic, and the empirical P-value was estimated using 20,000 permutations.
indicates significance at P<0.01.
indicates significance at P<0.05.