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. 2012 May 4;7(5):e36264. doi: 10.1371/journal.pone.0036264

Table 2. Family-based association analysis of nuclear SNPs with growth traits1 using the R package GWAF2.

SNP Weight2 Weight3 Weight4
χ2 DF P Model3 h2 q χ2 DF P Model3 h2 q χ2 DF P Model3 h2 q
nuSNP7 233.08 1 1.27E−52** D 0 81.86 1 1.46E−19** D 0 12.45 1 0.00041 D 0
nuSNP8 2.38 1 0.12291 D 0 33.25 1 8.10E−09* D 0 0.56 1 0.4539 D 0
nuSNP12 8.43 2 0.01478 G 0.01 21.21 2 0.00002* G 0.01 17.27 2 0.00017* G 0.01
nuSNP20 279.6 1 9.20E−63** D 0 101.75 1 6.31E−24** D 0 15.91 1 6.65E−05* D 0
nuSNP21 245.88 1 2.05E−55** D 0 101.14 1 8.59E−24** D 0 12.22 1 0.00047 D 0
1

Body weight was recorded on each animal at approximately 7 (Weight2), 9 (Weight3) and 12 (Weight4) months post-hatching.

2

The genome-wide association analysis with family data (GWAF) R package [23] was used in the association analysis. The analyzed sample included 40 full-sib families each with ∼17 progeny. Here, we show the asymptotic P-value for the test statistic distributed as a χ2 with 1 and 2 DF for dominant and general model, respectively. The Inline graphic is the proportion of phenotypic variance explained by the tested SNP.

3

The general (G) and dominant (D) models had the highest likelihood in the association analysis of Weight2, Weight3 and Weight4.

**

indicates SNPs strongly associated with BW (P-value = 1.5E−19 to 9.2E−63).

*

indicates SNPs with weaker association (P-value = 2.0E−5 to 8.1E−09).