Table 2. Family-based association analysis of nuclear SNPs with growth traits1 using the R package GWAF2.
SNP | Weight2 | Weight3 | Weight4 | ||||||||||||
χ2 | DF | P | Model3 | h2 q | χ2 | DF | P | Model3 | h2 q | χ2 | DF | P | Model3 | h2 q | |
nuSNP7 | 233.08 | 1 | 1.27E−52** | D | 0 | 81.86 | 1 | 1.46E−19** | D | 0 | 12.45 | 1 | 0.00041 | D | 0 |
nuSNP8 | 2.38 | 1 | 0.12291 | D | 0 | 33.25 | 1 | 8.10E−09* | D | 0 | 0.56 | 1 | 0.4539 | D | 0 |
nuSNP12 | 8.43 | 2 | 0.01478 | G | 0.01 | 21.21 | 2 | 0.00002* | G | 0.01 | 17.27 | 2 | 0.00017* | G | 0.01 |
nuSNP20 | 279.6 | 1 | 9.20E−63** | D | 0 | 101.75 | 1 | 6.31E−24** | D | 0 | 15.91 | 1 | 6.65E−05* | D | 0 |
nuSNP21 | 245.88 | 1 | 2.05E−55** | D | 0 | 101.14 | 1 | 8.59E−24** | D | 0 | 12.22 | 1 | 0.00047 | D | 0 |
Body weight was recorded on each animal at approximately 7 (Weight2), 9 (Weight3) and 12 (Weight4) months post-hatching.
The genome-wide association analysis with family data (GWAF) R package [23] was used in the association analysis. The analyzed sample included 40 full-sib families each with ∼17 progeny. Here, we show the asymptotic P-value for the test statistic distributed as a χ2 with 1 and 2 DF for dominant and general model, respectively. The is the proportion of phenotypic variance explained by the tested SNP.
The general (G) and dominant (D) models had the highest likelihood in the association analysis of Weight2, Weight3 and Weight4.
indicates SNPs strongly associated with BW (P-value = 1.5E−19 to 9.2E−63).
indicates SNPs with weaker association (P-value = 2.0E−5 to 8.1E−09).