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. 2012 May 4;7(5):e36264. doi: 10.1371/journal.pone.0036264

Table 6. Summary of mitochondrial markers significantly associated 1 with growth traits and their annotations1.

SNP Physical position (bp)2 MAF3 Annotation4 Location/amino acid change
mtSNP1 4116 0.49 NADH dehydrogenase subunit 1 ORF/SYN
mtSNP2 4323 0.49 NADH dehydrogenase subunit 1 ORF/SYN
mtSNP3 4647 0.48 NADH dehydrogenase subunit 1 ORF/SYN
mtSNP4 5212 0.48 NADH dehydrogenase subunit 2 ORF/SYN
mtSNP5 5275 0.48 NADH dehydrogenase subunit 2 ORF/SYN
mtSNP6 5530 0.48 NADH dehydrogenase subunit 2 ORF/SYN
mtSNP7 5740 0.49 NADH dehydrogenase subunit 2 ORF/SYN
mtSNP16 12423 0.47 NADH dehydrogenase subunit 4 ORF/V→ M
mtSNP17 13231 0.49 NADH dehydrogenase subunit 5 ORF/SYN
mtSNP18 13795 0.48 NADH dehydrogenase subunit 5 ORF/SYN
mtSNP19 14077 0.48 NADH dehydrogenase subunit 5 ORF/SYN
mtSNP20 14626 0.49 NADH dehydrogenase subunit 5 ORF/SYN
mtSNP21 15591 0.23 Cytochrome b ORF/SYN
mtSNP22 15822 0.49 Cytochrome b ORF/SYN
mtSNP23 16305 0.49 Cytochrome b ORF/SYN
mtSNP24 16317 0.48 Cytochrome b ORF/SYN
mtSNP8 7052 0.23 Cytochrome c oxidase subunit 1 ORF/SYN
mtSNP9 7193 0.50 Cytochrome c oxidase subunit 1 ORF/SYN
mtSNP10 8774 0.48 Cytochrome c oxidase subunit 2 ORF/SYN
mtSNP11 8804 0.48 Cytochrome c oxidase subunit 2 ORF/SYN
mtSNP14 9410 0.48 ATPase 6 ORF/SYN
mtSNP15 9656 0.49 ATPase 6 ORF/SYN
mtSNP12 9084 0.48 ATPase 8 ORF/SYN
mtSNP13 9087 0.49 ATPase 8 ORF/SYN
1

Body weight was recorded on each animal at approximately 7 (Weight2), 9 (Weight3) and 12 (Weight4) months post-hatching. Population-based association analysis was performed with program PLINK version 1.07 [22]. From 40 full-sib families each with ∼17 progeny, a sibling was randomly sampled from each family to generate a population-based sample of n = 40 unrelated individuals; we repeated the random sampling to develop three sets of unrelated individuals.

2

Markers were positioned on mitochondrial genome by BLASTing sequences flanking markers against a rainbow trout mitochondrial reference sequence [33].

3

SNPs minor allele frequency (MAF). 4SNP annotation; gene name and SNP location (ORF/5′UTR/3′UTR), SYN = Synonymous.