Figure 5. Alpha-adrenergic blockade disrupts long-term adaptation in NCM.

a) Schematic representation of the experimental design depicting exposure to training songs followed the next day (20–21 hr later) by electrophysiological recordings during playback of both familiar training songs and novel songs in control and phentolamine-injected hemispheres. b) Familiarity indexes (the ratio between adaptation rates for novel songs and songs heard by the animal 20–21 h earlier, see Methods) are shown for both the control and phentolamine-injected hemispheres.