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. 2012 May 4;7(5):e36482. doi: 10.1371/journal.pone.0036482

Table 1. Patient Characteristics.

Patient characteristics Early AVF dysfunction (n = 11) Late AVF dysfunction (n = 23) No AVF dysfunction (n = 34) p All patients (n = 68)
Mean age (years, ±SD) 68±12 60±15 61±16 0.33 62±15
Gender [n (%)] 0.87
Male 7 (63.6) 15 (65.2) 24 (70.6) 46 (67.6)
Female 4 (36.4) 8 (34.8) 10 (29.4) 22 (32.4)
Smoker [n (%)] 4 (36.4) 13 (56.5) 16 (47.1) 0.53 33 (48.5)
Other diseases [n (%)]
Heart failure 7 (70.0) 18 (81.8) 28 (84.8) 0.45 53 (81.5)
Diabetes 2 (22.2) 12 (54.5) 8 (25.8) 0.07 22 (35.5)
Hyperlipidemia 3 (33.3) 3 (13.6) 8 (25.8) 0.41 14 (22.6)
Hypertension 7 (70.0) 18 (81.8) 28 (84.8) 0.57 53 (81.5)
Medications [n (%)]
Antithrombotic agents 2 (20.0) 8 (34.8) 12 (40.0) 0.52 22 (34.9)
Anticoagulative agents 1 (11.1) 0 (0.0) 1 (3.3) 0.28 2 (3.2)
β blockers 4 (40.0) 18 (78.3) 23 (74.2) 0.07 45 (70.3)
Calcium antagonists 4 (40.0) 15 (65.2) 24 (77.4) 0.09 43 (67.2)
ACEI 3 (30.0) 11 (47.8) 14 (45.2) 0.62 28 (43.8)
Statins 2 (22.2) 9 (39.1) 15 (48.4) 0.36 26 (41.3)
Biochemical parameters
C-reactive protein (mg/L, ± SD) 18.6±16.8 8.6±7.7 7.3±6.6 0.01 9.2±9.3
Procalcitonin (ng/L, ± SD) 0.24±0.08 0.19±0.07 0.21±0.06 0.24 0.21±0.07
HDL cholesterol (mg/dL, ± SD) 52.1±18.5 50.8±18.0 56.7±17.6 0.54 54.2±17.7
LDL cholesterol (mg/dL, ± SD) 108.6±48.1 104.5±53.1 99.5±45.7 0.89 102.4±47.7
Triglyceride (mg/dL, ± SD) 158.4±75.8 152.4±97.1 148.6±82.4 0.96 151.1±85.2
Creatinine (mg/dL, ± SD) 5.2±1.9 4.6±1.4 5.1±1.9 0.74 5.1±1.8
Albumin (g/dL, ± SD) 3.2±1.1 3.6±0.6 4.0±0.4 0.003 3.8±0.7
Albumin corrected calcium (mg/L, ± SD) 8.7±0.6 8.2±0.7 8.6±0.4 0.09 8.5±0.6
White blood cell count (109 cells/L, ± SD) 9.3±2.3 7.2±1.9 7.1±1.7 0.01 7.4±2.0
Neutrophils (109 cells/L, ± SD) 6.2±2.6 4.8±1.6 4.6±1.2 0.06 4.9±1.6
Lymphocytes (109 cells/L, ± SD) 1.6±0.3 1.8±0.8 1.6±0.7 0.41 1.7±0.7
Monocytes (109 cells/L, ± SD) 0.7±0.2 0.6±0.2 0.7±0.3 0.22 0.7±0.3
Hematocrit (%, ± SD) 28.7±3.0 30.8±3.6 32.3±4.5 0.07 31.3±4.1
Red blood cells (×1012/L, ± SD) 3.2±0.3 3.5±0.4 3.7±0.6 0.048 3.5±0.5
Hemoglobin (g/dL, ± SD) 9.7±1.0 10.4±1.4 10.9±1.5 0.08 10.6±1.5
MCV (fL, ± SD) 89.4±2.6 89.3±7.7 89.1±4.7 0.99 89.2±5.8
MCH (pg, ± SD) 30.1±1.4 30.2±3.1 30.4±2.0 0.93 30.3±2.4
RDW (%, ± SD) 16.9±2.4 15.6±2.3 14.8±1.7 0.03 15.4±2.1
Platelets (×103/µL, ± SD) 329±143 231±80 257±89 0.049 257±98
Iron (µmol/L, ± SD) 10.9±3.9 11.5±5.7 11.5±6.9 0.96 11.4±6.1
Transferrin (g/L, ± SD) 1.8±0.3 1.9±0.5 1.8±0.5 0.77 1.8±0.4
Ferritin (µg/L, ± SD) 170.4±104.7 189.3±202.6 235.7±314.5 0.69 209.4±254.1

Boldface indicates statistically significant values (p<0.05). ACEI, angiotensin-converting enzyme inhibitor; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; RDW, red blood cell distribution width.