Table 2. Results of Univariable and Multivariable Analyses.
| Patient characteristics | Univariable analysis HR (95% CI) | p | Multivariable analysis | p |
| Age (y) | 1.01 (0.98 to 1.03) | 0.517 | ||
| Male | 0.90 (0.45 to 1.82) | 0.780 | ||
| Smoking | 1.03 (0.53 to 2.01) | 0.934 | ||
| Other diseases | ||||
| Heart failure | 1.46 (0.74 to 2.88) | 0.280 | ||
| Diabetes | 1.58 (0.78 to 3.19) | 0.207 | ||
| Hyperlipidemia | 0.85 (0.35 to 2.06) | 0.716 | ||
| Hypertension | 0.65 (0.28 to 1.51) | 0.323 | ||
| Medications | ||||
| Antithrombotic agents | 0.74 (0.35 to 1.56) | 0.433 | ||
| Anticoagulative agents | 1.23 (0.17 to 8.95) | 0.838 | ||
| β blockers | 0.68 (0.33 to 1.40) | 0.300 | ||
| Calcium antagonists | 0.52 (0.26 to 1.03) | 0.061 | ||
| ACEI | 0.88 (0.44 to 1.75) | 0.722 | ||
| Statins | 0.67 (0.32 to 1.38) | 0.278 | ||
| Biochemical parameters | ||||
| C-reactive protein (mg/L, ± SD) | 1.04 (1.00 to 1.08) | 0.040 | 1.00 (0.95 to 1.05) | 0.895 |
| Procalcitonin (ng/L, ± SD) | 0.23 (0.00 to 65.00) | 0.609 | ||
| HDL cholesterol (mg/dL, ± SD) | 0.99 (0.96 to 1.01) | 0.367 | ||
| LDL cholesterol (mg/dL, ± SD) | 1.00 (0.99 to 1.01) | 0.637 | ||
| Triglyceride (mg/dL, ± SD) | 1.00 (1.00 to 1.01) | 0.893 | ||
| Creatinine (mg/dL, ± SD) | 0.99 (0.81 to 1.21) | 0.913 | ||
| Albumin (g/dL, ± SD) | 0.43 (0.26 to 0.71) | 0.001 | 0.61 (0.32 to 1.16) | 0.137 |
| Albumin corrected calcium (mg/L, ± SD) | 0.60 (0.30 to 1.19) | 0.145 | 0.50 (0.22 to 1.12) | 0.094 |
| White blood cell count (109 cells/L, ± SD) | 1.22 (1.00 to 1.49) | 0.048 | 1.67 (1.24 to 2.25) | <0.001 |
| Neutrophils (109 cells/L ± SD) | 1.31 (0.99 to 1.72) | 0.056 | ||
| Lymphocytes (109 cells/L ± SD) | 1.17 (0.71 to 1.93) | 0.553 | ||
| Monocytes (109 cells/L ± SD) | 0.31 (0.07 to 1.43) | 0.040 | 0.02 (0.00 to 0.21) | 0.001 |
| Hematocrit (%, ± SD) | 0.92 (0.84 to 1.00) | 0.062 | ||
| Red blood cells (×1012/L, ± SD) | 0.46 (0.22 to 0.96) | 0.040 | 0.98 (0.25 to 3.89) | 0.973 |
| Hemoglobin (g/dL, ± SD) | 0.79 (0.61 to 1.01) | 0.066 | ||
| MCV (fL, ± SD) | 1.01 (0.94 to 1.07) | 0.866 | ||
| MCH (pg, ± SD) | 0.96 (0.83 to 1.12) | 0.645 | ||
| RDW (%, ± SD) | 1.18 (1.02 to 1.37) | 0.029 | 1.44 (1.17 to 1.78) | <0.001 |
| Platelets (×103/µL, ± SD) | 1.00 (1.00 to 1.00) | 0.843 | ||
| Iron (µmol/L, ± SD) | 0.99 (0.94 to 1.05) | 0.849 | ||
| Transferrin (g/L, ± SD) | 1.03 (0.48 to 2.19) | 0.947 | ||
| Ferritin (µg/L, ± SD) | 1.00 (1.00 to 1.00) | 0.516 |
Boldface indicates statistically significant values (p<0.05). ACEI, angiotensin-converting enzyme inhibitor; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; RDW, red blood cell distribution width.