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. 2012 May 4;7(5):e36476. doi: 10.1371/journal.pone.0036476

Figure 3. Duloxetine prevented the acute emotional effects of MDMA in the Adjective Mood Rating Scale.

Figure 3

MDMA produced a state of well-being (a), emotional excitation (b), increased introversion at drug onset at 1.25 h (d), increased extroversion at 2 h (c), increased dreaminess (e), and decreased performance-oriented activity (f) (*p<0.05, **p<0.01, ***p<0.001, vs. placebo-placebo). Duloxetine prevented MDMA-induced elevations in well-being, emotional excitation, and extroversion (a-c) (### p<0.001, placebo-MDMA vs. duloxetine-MDMA). Values are expressed as mean+SEM (n  = 16).