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. 2012 May 4;7(5):e36476. doi: 10.1371/journal.pone.0036476

Figure 4. Duloxetine prevented the acute effects of MDMA in the Altered States of Consciousness (ASC) scale.

Figure 4

MDMA significantly increased the ASC sum score, Oceanic Boundlessness (OB), Anxious Ego Dissolution (AED), and Visionary Restructuralization (VR) dimensions, and most of the subscales (*p<0.05, **p<0.01, ***p<0.001, placebo-placebo vs. placebo-MDMA). Duloxetine significantly reduced the effect of MDMA in all dimensions and subscales (#p<0.05, ##p<0.01, ###p<0.001, placebo-MDMA vs. duloxetine-MDMA). Values are expressed as mean+SEM (n  = 16).